recombination frequency is (higher/lower) when the linked genes are further away
Back
deletion
Front
change to a chromosome in which a fragment of the chromosome is removed
Back
crossing over
Front
process in which homologous chromosomes exchange portions of their chromatids during meiosis
Back
recombinant types
Front
when offspring display phenotypes that are different than parents
Back
monosomic
Front
A chromosomal condition in which a particular cell has only one copy of a chromosome
Back
genomic imprinting
Front
a phenomenon in which expression of an allele in offspring depends on whether the allele is inherited from the male or female parent; always needs one active copy (not 2 or 0)
Back
inversion
Front
change to a chromosome in which a fragment of the original chromosome is reversed
Back
histones and methyl groups
Front
how are X-chromosomes inactivated in females
Back
Errors in meiosis or damaging reagents such as radiation
Front
What can alter the chromosome structure?
Back
Klinefelter syndrome
Front
a chromosomal trisomy in which males have an extra X chromosome resulting in an XXy condition; affected individuals typically have reduced fertility
Back
Thomas Hunt Morgan
Front
Biologist provided more evidence to the theory of Chromosomal Basis of Inheritance studying sex-linked traits in fruit flies.
Back
plant
Front
Polyploidy is common in what kingdom?
Back
mitochondrial
Front
the reason you have more DNA from your biological mother than your biological father; endosymbiosis theory
Back
chi-square
Front
a statistic used to measure how much a sample distribution differs from a theoretical distribution
Back
parental types
Front
offspring with a phenotype that matches one of the parental phenotypes.
Back
+
Front
superscript for wild-type
Back
Down syndrome
Front
A human genetic disease resulting from having an extra chromosome 21, characterized by mental retardation and heart and respiratory defects.
Back
Chromosome theory of inheritance
Front
Mendelian genes have specific loci on chromosomes, and it is the chromosomes that undergo segregation and independent assortment during meiosis.
Back
genetic map
Front
an ordered list of the genetic loci along a particular chromosome.
Back
recombination frequency
Front
proportion of recombinant progeny produced in a cross
Back
linked gene
Front
Genes located close enough together on a chromosome to be usually inherited together.
Back
aneuploidy
Front
A chromosomal aberration in which one or more chromosomes are present in extra copies or are deficient in number.
Back
down syndrome
Front
trisomy 21
Back
polyploidy
Front
a chromosomal alteration in which the organism possesses more than two complete chromosome sets.
Back
Only four chromosomes
Front
An advantage of testing fruit flies
Back
Chromosomal systems of sex determination
Front
1) XY system in mammals
2) X0 system in insects
3) ZW system in birds and some insects (opposite of XY)
4) Haplo-diplo system in bees and ants
Back
linkage map
Front
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes.
Back
trisomic
Front
A chromosomal condition in which a particular cell has an extra copy of one chromosome, instead of the normal two; the cell is said to be trisomic for that chromosome.
Back
wild type
Front
The phenotype for a character most commonly observed in natural populations
Back
duplication
Front
change in chromosome structure in which a particular segment is present more than once in the same chromosome
Back
X-linked genes
Front
A gene located on the X chromosome; such genes show a distinctive pattern of inheritance.
Back
cri du chat
Front
a chromosomal deletion in chromosome 5 that results in children who are mentally retarded, have small heads, and have a cry that sounds like a loud cat; they die at a young age
Back
genetic recombination
Front
the production of offspring with combinations of traits differing from those found in either parent
Back
Polyploids
Front
Which are more normal polyploids or aneuploids?
Back
Turner syndrome
Front
Chromosome disorder in females. a x chromosome is missing or part of one x is deleted. short stature
Back
chloroplast DNA
Front
non-nuclear DNA; endosymbiosis theory that chloroplasts evolved from free living prokaryotes
Back
XIST
Front
Gene responsible for X-inactivation; located on the long arm of the X-chromosome
Back
Barr body
Front
A dense object lying along the inside of the nuclear envelope in female mammalian cells, representing an inactivated X chromosome.
Back
mutant phenotypes
Front
due to alleles assumed to have originated as changes, or mutations, in the wild-type allele
Back
cytoplasmic genes
Front
Genes found in organelles other than the nucleus (chloroplasts and mitochondria). It is maternally inherited, since the egg donates the cytoplasm to the zygote in fertilization.
Back
sex-linked gene
Front
A gene that is carried on the X or Y chromosome
Back
0.05
Front
If the probability of the X^2 value is _______ or less it means the genes are linked (reject hypothesis that the genes are unlinked)
Back
hemophilia
Front
an X-linked recessive disorder in which blood fails to clot properly, leading to excessive bleeding if injured.
Back
map units
Front
a measurement of the distance between genes; one map unit is equivalent to a 1 percent recombination frequency.
Back
X-linked
Front
color blindness is a ____ trait
Back
Duchenne muscular dystrophy
Front
X-linked; affects about 1 in 3,500 males; results from absence of a key muscle protein called dystrophin
Back
translocation
Front
change to a chromosome in which a fragment of one chromosome attaches to a nonhomologous chromosome
Back
nondisjunction
Front
the failure of homologous chromosomes to separate during meiosis I or the failure of sister chromatids to separate during mitosis or meiosis II