a cell brings in biological molecules and particulate matter by forming new vesicles from the plasma membrane.
3 types: phagocytosis, pinocytosis and receptor-mediated endocytosis.
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. A proton pump is
Front
the most common electrogenic pump in plants, bacteria and fungi, and it is responsible for pumping protons from the inside of the cell to the extracellular environment.
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sodium-potassium pump
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transport protein that, translocating the bound solute across the membrane. Exchanges sodium ions (Na) for potassium ions (K) across the plasma membrane of animal cells.
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pinocytosis
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molecules are taken up when extracellular fluid is "gulped" into tiny vesicles.
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tonicity
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the ability of a surrounding solution to cause a cell to gain or lose water.
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turgid
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when the plant cell is very firm, which is a healthy state for most plant cells.
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lipoproteins
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complexes of proteins and lipids. Cholesterol travels in low density _______
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fluid mosaic model
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The arrangement of phospholipids and proteins in biological membranes is described by the...
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hypotonic (animal cell)
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when a cell is immersed in a solution, water enters the cell faster than it leaves, it swells and lyses (explodes) like an overfilled water balloon.
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plasmolysis
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This happens when a cell shrinks inside its cell wall while the cell wall remains intact. The plasma membrane pulls away from the wall.
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aquaporins
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channel proteins that facilitate the passage of water
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isotonic (animal cell)
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if a cell with no cell wall is immersed in an enviroment where there is no net movement of water across the plasma membrane. Stays the same.
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cell-cell recognition
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the ability of a cell to disitnguish one type of neighboring cell from another.
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concentration gradient
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the region along which the density of a chemical substance increases or decreases.
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exocytosis
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transport vesicle budded from the Golgi apparatus is moved by the cytoskeleton to the plasma membrane. When the 2 membranes come in contact, the bilayers fuse spill the contents.
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active transport
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transport that requires the cell to expend metabolic energy and enables a cell to maintain internal concentrations of small molecules. Requires energy.
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hypotonic (plant cell)
Front
when a plant cell is immersed in a __________ solution the cell contents swell due to osmosis until the elastic cell wall exerts turgor pressure on the cell that opposes further water outake.
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phagocytosis
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a cell engulfs a particle in a vacuole. The vacuole fuses with a lysosome to digest the particle.
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hypertonic (plant cells)
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the plant cell loses water, its volume shrinks. The plasma membrane pulls away from the wall, this is plasmolysis. It is lethal to the cell.
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osmoregulation
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the control of water balance
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membrane potential
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voltage across a membrane. Ranges form -50 to -200 millivolts. The inside of the cell is negative to the outside.
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amphipatic molecules
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have hydrophobic and hydrophilic regions
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channel proteins
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transport proteins that have a hydrophilic channel that certain molecules or ions use as a tunnel though the membrane.
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isotonic (plant cell)
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when a plant cell is immersed in a _______ solution; there is no net movement. The cell becomes flaccid and the plant may wilt.
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diffusion
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movement of molecules of any substance to spread out in available space
passive transport
high to low down concentration gradient decreas freee energy
- delta G
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facilitated diffusion
Front
the passive movement of molecules down their concentration gradient with the help of transport proteins.
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receptor-mediated endocytosis
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endocytosis that enables a cell to acquire bulk quantities of specific materials that may be in low concentrations in the environment.
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ion channels (gated channels)
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Channels that open or close depending on the presence or abscence of an electrical, chemical, or physical stimulus.
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hypertonic (animal cell)
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when the cell is immersed in a solution where it loses water to its environment, shrivels and probably dies.
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carrier proteins
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transport proteins that bind to molecules and change shape to shuttle them across the membrane.
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electrochemical gradient
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2 combined forces drive the diffusion of ions across the membrane.
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An electrogenic pump is
Front
a transport protein that generates voltage across a membrane by transporting more ions in one direction than the other
generates a membrane potential, and the membrane potential leads to an electrochemical gradient.
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integral proteins
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proteins that penetrate the hydrophobic interior of the lipid bilayer
reach partway or completely through membrane with hydrophilic ends + hydrophobic middle
attach ECM to P.M
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flaccid
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limp, not firm or strong (If a plant is not watered enough, its leaves become droopy and flaccid.)
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ATP
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supplies energy for most active transport
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peripheral proteins
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proteins that are not embedded in the lipid bi layer
they are attached to cytosol side of integral proteins ( not embedded)
held in place by cytoskeleton
maintain cell shape + fix location of proteins
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sodium-potassium pump
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major electrogenic pump in animals. Restores the electrochemical gradient by setting up a concentration gradient. It pumps 2 K ions for every 3 Na ions that it moves out, it generates a voltage.
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proton pumps
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the major electrogenic pump. Transports protons out of the cell and transfers positive charge form the cytoplasm to the extracellular solution.
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transmembrane proteins
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the integral protein completely spans the membrane as...
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lipids and proteins
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main macromolecules in membranes
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passive transport
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transport that requires no energy from the cell to make it happen
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osmosis
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the diffusion of water across a selectively permeable membrane
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cystinuria
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human disease characterized by the absence of a carrier protein that transports cysteine and other amino acids across the membranes of kidney cells.
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Paramecium
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is a protist that is hypertonic to the pond water in which it lives.
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selectively permeable
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allows some substances to cross more easily than others.
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phospholipids
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most abundant lipids
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plasma membrane
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separates the living cell from its surroundings. Controls traffic in and out of the cell. Is selectively permeable.
bifacial- has distinct cytoplasmic + EC side
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electrogenic pumps
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special transport proteins that generate the voltage gradient across a membrane.
Ex. sodium potassium pump and proton pumps.
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cotransport
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single ATP-powered pump that transports a specific solute can indirectly drive the active transport of several other solutes in a mechanism.
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freeze-fracture
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preparation technique that splits a membrane along the middle of the phospholipid bilayer
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Section 2
(32 cards)
uniport
Front
carries a single aolute acrocc th emrenbrane
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lections
Front
a phospholipid both with glycerol backbone + 2 fatty acids
Attach a nitrogenous base called ethanolamine
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peremability of p m depends on
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bilayer charactceristiccs
non polar hydrophillic molecules dissolve in membrane + cross easily smaller ones move faster
Transport proteins
allow hydrophilic ions _ polar molecules to pass specfic channel for pspectifc molecules
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Langmuir 1917
Front
Amphiphilic phospholipids will form a artificial membrane on wa water surface with hydrophilic heads immersed in water + hydrophobic tails excluded
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dialysis
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movement of particles in a solution through permeable membranes. The diffusion of small solutes through a selectively permeable membrane.
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osmotic pressure sloute potenitla
Front
puul ot push on H2o into ot out of an area
dretctly proportoinla to # of lsoute partilces
the more particles the greater osmotic pressure
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cell to cell recognition
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ability of a cell to determine if other cells are alike or different from itself
use glycoproteins and glycolipids as ID tags
also used to sort embryo cells into tissues
for rejection of foreign cells by immune system Ex- RBC A B AB o each has a different oligosacharide
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symport
Front
moves 2 @ the same time in same direction
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water balance plant cells
Front
hyper H2O out p.m + cytoplasm shrivels
plasmolysis
hypo h2o in swells plump cell ( turgid)
rigid cell
turgor pressure becomes greater than an osmotic pressure that brings H2O in ( 1st equilibrium) then H2o will actually be pushed out if cell by turgor pressure
iso no water gain or loss flaccid-limp
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Enzymes
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active site exposed to ECF substances
several in a membrane function as o metabolic pathway
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transport protein
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a channel spanning the membrane selective for a solute
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entropy
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a meaure of disorganiztion or chatoic state of a system
univers goes from low to high enthropy
the purer the h2o the more organised the lower the entropy
h2 o moves from low to high entrophy
low enthrophy - sugar cube
high- sugar cub dissolved in cup of water
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water balance aniamal cells
Front
hypo + solvent-solute
cytolysis- cell destruction
iso solvent = solute
hyper - solvent + solute
cell shrinks crenation or RBC hemolysis
osmoregulation in parameicum- contractile vacuoles
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Membrane potential is
Front
the voltage across a membrane, the result of the separation of opposite charges.
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diffusion entropy
Front
low to high
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ligands
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A molecule that binds specifically to a receptor site of another molecule.
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Cepalins
Front
a phospholipid both with glycerol backbone + 2 fatty acids
Attach a nitrogenous base called ethanolamine
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ethaply free energy
Front
an indication of the eprotinal ( store enregy of a syetem available for work.
the purere the H2O the greater the enthalpy
the more solutes particles in H2o , the lowr the enthaply
h2o moves froma state of high to low ethaply
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inter cellular junctions
Front
adhere adjacent cells
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integral proteins functions
Front
transport proteins, enzymes, Receptor sites cell to cell recogonition
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cholesterol
Front
wedged into the phospholipid animal membranes, hinders close packing at lower temps
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osmostic concentrion
Front
# if particles in a solution affect osmosis
H2o moves from low osmotic conc. (High H2o Conc.) to high osmotic conc. ( Low H2o Conc.)
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anitport
Front
exchanges two solutes in opposite directions
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water potenial
Front
a measure of the potential energy in water as well as the difference between the potential in a given water sample and pure water
add solute particles to h2o - megative #'s
h2o moves frmo high to low
lower solute concenraion to high sloute concentraion
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water will move from
Front
high H2O potenital (hypo) to low H2o potenial ( hyper)
low solute to higher soulte
hypo to hyper
low osmotic- hypo to high osmotic-
hyper potential
high free energy to low
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receptor sites
Front
expose a binding site fro specific chemical messenger ( neurotransmitter or hormones)
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Electrochemical gradient is
Front
a combination of two forces on an ion: the first one is chemical force (the ion's concentration gradient), the second one is an electrical force (the result of the membrane potential).
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membrane is held together by
Front
weak hydrophobic interactions
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Esterification
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making of an ester bridge from an alcohol and acid
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Overton 1895
Front
Substances that dissolve in lipids enter cells more rapidly than those insoluble in lipids
deduction- membranes are made of lipids
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osmotic potenial
Front
the tendency of a s,oution to gain h2o kots of solutes wiil suck waer in to it