- produces both A & B antigens on red blood cells
- blood contains NEITHER anti-A nor anti-B antibodies
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timing of meiosis
Front
as eggs age with the mom, errors in chromosome number can occur
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type A
Front
- produce A markers (antigens) on the surface of every red blood cell
- blood contains anti-B antibodies
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inheritance of alleles
Front
place of one particular gene on a chromosome - locus
- homologous chromosomes have corresponding loci, but they may or may not contain matching alleles
product of one egg + one sperm = one zygote (one set of DNA, so they are 100% genetically identical) (same alleles)
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simple, recessive disorder
Front
cystic fibrosis (defective protein thickens mucus)
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type B
Front
- produces B antigens on red blood cells
- blood contains anti-A antibodies
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trisomy
Front
3 copies of a chromosome (in every somatic cell)
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type O
Front
- produces neither A nor B antigens (no markers)
- blood contains BOTH anti-a and anti-B antibodies
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antibodies
Front
Y shaped proteins circulating in blood are produced by white blood cells, dock with specific antigens on foreign cells/objects to defend against them by clumping them together for destruction by other white blood cells
- Y's hook on and clump (bacteria) big white blood cells come and destroys it
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"simple" inheritance
Front
only one gene involved, no environmental factors that are relevant, and only 2 alleles exist (one dominant, one recessive)
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sickle cell anemia
Front
- simple recessive inherited disorder
- defective protein in red blood cells
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positive blood type
Front
- have Rh antigens on red blood cells
- can receive blood from BOTH positive and negative donors
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dizygotic twins "fraternal"
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separate eggs fertilized by/fused with separate sperm -- 2 zygotes
- same genetic similarity as any regular sibling (50%)
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antigens
Front
markers on cell surfaces
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crossing over
Front
exchange of corresponding portions of homologous chromosomes
- produces chromosomes that contain mixtures of alleles from the individual's parents
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negative blood type
Front
- lack Rh antigens on red blood cells, so the white blood cells produce anti-Rh antibodies
- cannot receive blood from a positive donor
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trisomy 21
Front
Down syndrome (least severe error in chromosome number, but still significant)