full thickness burn
destroys epidermis, dermis, and the epidermal derivitaves
burned area appears blanched (gray-white) or blackened with very little if any edema
area around the burn shows symptoms of lesser degree burns
Back
Second Degree Burn
Front
burn that damages deep epidermis and upper dermis
shows same symptoms as first degree burn but produces bullae (water filled blisters)
Back
Stratum Corneum
Front
layer of 25 to 30 rows of flat, dead, keratinized cells
this layer flakes off
Back
Dermis
Front
thicker connective tissue layer
tough but flexible loose connective tissue layer composed of a gel-like matrix heavily embedded with collagen, elastin, and reticilin fibers
Back
Platelet (Thrombocyte)
Front
formed element of the blood which contains an enzyme for clotting known as thromboplastin
Back
Eponychium (Cuticle)
Front
narrow band of epidermis that occupies the proximal border of the nail and consists of stratum corneum
Back
End bulbs of Krause
Front
dermal cold receptors
Back
Hair Structure
Front
Shaft - superficial portion which projects above the skin surface which has three principle parts (medulla - inner region, cortex - middle layer, and cuticle - outer layer)
Root - hair below the dermis and subcutaneous layer
Bulb - enlarged base of the hair containing an indentation called the papilla and contains the matrix (germinal layer or growth region of the hair)
Back
Third Stage of the Inflammatory Response
Front
3. Release of nutrients - nutrients are needed to fight antigens and repair damage
Back
Granulation
Front
new cells originate from cells of the stroma and parenchymal cells from the functioning parts of the tissue or organ
Back
Fifth Stage of the Inflammatory Response
Front
Pus formation - thick fluid containing living and non-living white cells plus debris from dead and damaged tissue accumulates (abscess or ulcer)
Back
Keratinocytes
Front
produce keratohaline (eventually keratin)
Back
Fibrosis
Front
formation of scar tissue
Back
Step 5 of Blood Clotting
Front
5. syneresis occurs
syneresis is clot retraction and shrinkage which serves to bring the edges of torn tissue together
Back
Stratum Germinativium
Front
what the stratum basale and stratum spinosum are usually called together
Back
Nails
Front
modified horny cells of the epidermis
nail consists of a nail body, free edge, and the nail root
most of the nail body is pink due to the underlying vascular tissue except for the whitish semilunar area at the proximal end known as the lunula
Back
First Degree Burn
Front
burn that damages only the epidermis
symptoms are localized redness, edema, and pain
Back
First Stage of the Inflammatory Response
Front
1. Vasodilation and increased permeability of blood vessels - produces heat, redness, and swelling (edema) - caused by the release of histamines primarily from mast cells, and some from basophils and platelets - kinins from the blood plasma increases the permeability of the vessels and attracts neutrophils - stage allows the clotting elements into the injured area
Back
Fourth Stage of the Inflammatory Response
Front
4. Fibrin formation - fibrinogen precipitates out as fibrin (protein fibers) which localizes and traps invading organisms and debris - eventually forms fibrin clot that prevents hemorrhage and isolates the infected area
Back
Step 6 of Blood Clotting
Front
6. fibrinolysis - the dissolving away of the old clot and some scar tissue
Back
Root Hair Plexus
Front
nerve net around the hair follicle for tactile sense of the hair
especially in vibrissae
Back
Hair
Front
Lanugo (fetal hair) - usually shed prior to birth except in the regions of the eyebrows, eye lashes, and scalp
Vellus (fleece) - facial and body hair
Terminal Hairs - coarse hair of scalp, eyebrows, and pubic hair
Back
Plasma Inclusions
Front
vitamin K - coenzyme for blood clotting by initiating the synthesis of prothrombin
calcium ions - Ca+ ions are involved in all stages of blood clotting while removal or binding of Ca+ prevents clotting
Back
Papillary Layer
Front
upper thin layer which forms the dermal papillae which protrude into the lower region of the dermis
containing capillary loops
results in the friction ridges on our fingers known as finger prints
Back
Sudoriferous or Sweat Glands
Front
simple, coiled, tubular glands
produce perspiration which is a mixture of water, salts, urea, uric and amino acids, ammonia, sugar, lactic acid, and other wastes
aids in secretion of waste products and regulating body temperature
Back
Stratum Basale
Front
single layer of columnar cells capable of mitosis which produces new skin cells (germinal layer)
Back
Stratum Spinosum
Front
8 to 10 rows of polyhedral cells with spine-like projections, sometimes called Prickle cells
Back
Step 2 of Blood Clotting
Front
2. thromboplastin activates prothrombin which then becomes thrombin
Back
Step 4 of Blood Clotting
Front
4. fibrin fibers stick together and form a fibrin net which forms fibrin/blood cell clot
Back
Epidermis
Front
epithelial layer
Back
Second Stage of the Inflammatory Response
Front
2. Phagocytic migration - white cells (leukocytes) known as neutrophils and monocytes migrate to the injured area in response to the kinins - monocytes become phagocytic macrophages
Back
Pacinian Corpuscle
Front
deep pressure or crude touch receptors of the dermis
Back
Stretch Marks
Front
silvery white scars call striae caused by rapid growth causing a tearing in the dermis and in some pregnancies
Back
Skin (Cutis)
Front
largest organ of the body
thickest on the dorsal and extensor surfaces and thinner on the ventral and flexor surfaces
Back
Step 3 of Blood Clotting
Front
3. thrombin reacts with the soluble fibrinogen causing the formation of fibrin fibers
Back
Sebaceous or Oil Glands
Front
simple, branched acinar or alveolar gland
secrete sebum (oil) which is a mixture of fats, cholesterol, proteins, and inorganic salts
keeps our skin and hair from drying out and aids in "water proofing"
infections may cause oil build up which leads to blackheads and pimples
Back
Step 1 of Blood Clotting
Front
1. platelets come in contact with collagen fibers in injured area and rupture releasing thromboplastin
Back
Meissner's Corpuscle
Front
"fine touch" receptor (not as sensitive as Merkel's discs) located within the papillary region of the dermis
Back
Nail Matrix
Front
epithelium of the proximal part of the nail bed which is the growth region of the nail
Back
Stratum Lucidum
Front
translucent layer containing a translucent material called eleiden (not present in hairy skin)
Back
Reticular Layer
Front
typical dense irregular connective tissue that contains bundles of interlocking collagen fibers that run in various planes parallel to the skin forming lines of cleavage, tension lines, and flexure lines
Back
Stratum Granulosum
Front
2-3 layers of flattened cells where keratinization occurs due to the accumulation of keratohaline
Back
Free Nerve Endings
Front
sensory for pain located within the dermis
Back
Blood Clotting
Front
coagulation of the blood
may be extrinsic or intrinsic
Back
Plasma Proteins
Front
soluble fibrinogen - soluble protein produced by the liver which becomes fibrin during blood clotting
prothrombin (inactivated thrombin) - soluble protein produced by the liver
Back
Nail Fold
Front
fold of skin beneath the nail bed and the furrow between the two is the nail groove
Back
What are the functions of skin?
Front
The skin functions to protect, maintain body temperature, pick up stimuli, synthesize Vit. D, excrete wastes, keep the body from losing water, and hold the body together.
Back
Merkel's Discs
Front
most sensitive of the "fine touch" receptors of the skin
only receptor located in the stratum germinativium of the epidermis
Back
Hyponichium
Front
thickened area of stratum corneum below the free edge of the nail
Back
Melanocytes
Front
produce skin pigments like melanin
Back
Section 2
(14 cards)
Genital Herpes
Front
herpes simplex II
caused by contact
Back
Contact Dermatitis
Front
skin inflamation
Back
Shingles
Front
herpes zoister
similar to chicken pox
Back
Psoriasis or Eczema
Front
dry, itchy, or flaky skin
Back
Warts
Front
viral tumors of the skin
nonmalignant and noncarcinogen
Back
Impetigo
Front
staph infection
Back
Squamous Cell Carcinoma
Front
prickle cell carcinoma
alteration in the stratum spinosum or prickle cells
not as common and more malignant than basal cell carcinoma
Back
Ruffini's Corpuscles
Front
dermal heat receptors
Back
Vitiligo
Front
genetic disorder
white patches of skin
Back
Skin Cancer
Front
caused by carcinogens or mutagens like UV radiation
Back
Basal Cell Carcinoma
Front
most common but least malignant
alteration of cells in the stratum basalae
Back
Malignant Melanoma
Front
rarest skin cancer but highly malignant and deadly
alteration of cells in highly pigmented areas such as moles and areas of melanocytes