Rapid weight loss
Recurring fever or profuse night sweats
Extreme and unexplained tiredness
Prolonged swelling of the lymph glands
Diarrhea that lasts for more than a week
Sores of the mouth, anus, or genitals
Red, brown, pink, or purplish blotches on or under the skin or inside the mouth, nose, or eyelids
Memory loss, depression, and other neurologic disorders.