Rule out: if have pain relief best with rest (NEG LR: 0.11)
Rule in: If POS for H/O of CA and 1 or more of the following: age >50 yrs, unexplained weight loss, failure to improve with 1 month conservative treatment,no relief with bedrest, recommend lab workup for ESR. POS LR 67.
If ESR > 50 mm/hr POS, then recommend advanced diagnostic imaging/ biopsy.
If ESR >50 mm/hr NEG, then recommend conservative radiographs
If conservative radiographs are NEG, STOP
If conservative radiographs are POS, then order advanced diagnostic imaging/ biopsy