As ribosome moves, two tRNA with their amino acids move into site A and P of the ribosome
Peptide bonds join the amino acids
Back
Messenger RNA (mRNA)
Front
copies DNA's code & carries the genetic information to the ribosomes
Back
Silent mutation
Front
involve a chemical change in one base,
but do not change the protein.
Back
During transcription, RNA polymerase binds to DNA and separates the DNA strands
RNA Polymerase then uses one strand of DNA as a
template to assemble nucleotides into RNA
Front
Describe the steps of TRANSCRIPTION
Back
causes of mutation
Front
Radiation (X rays)
UV light
Mutagens (chemicals)
Back
Nonsense mutation
Front
Cause translation to terminate early
results in a premature stop codon.
Back
RNA
Front
Sugar ribose
Base Uracil (U)
Single stranded
CAN leave nucleus
Back
Silent mutation
Front
Changed DNA still produces the proper amino acid
does NOT result in a change in protein
Back
Promoters
Front
regions on DNA that show where RNA
Polymerase must bind to begin the Transcription of
RNA
Back
Ribosomal RNA (rRNA)
Front
along with protein, makes up the ribosomes
Back
Initiation
Front
mRNA transcript start codon AUG attaches to the small ribosomal subunit
Small subunit attaches to large ribosomal subunit
Back
initiation, elongation, termination
Front
What are the 3 steps of translation?
Back
missense, nonsense, and silent
Front
what are the 3 types of point mutation?
Back
mutation
Front
A permanent change in a cell's DNA. This leads to
mistakes in Protein Synthesis.
Back
DNA to RNA to protein
Transcription and Translation
Front
central dogma
Back
Insertion and deletion
Front
What are the two types of frameshift mutation?
Back
AUG
Front
methionine, start codon
Back
Transfer RNA (tRNA)
Front
transfers amino acids to the ribosomes where proteins are synthesized
Back
UAA, UAG, or UGA
Front
stop codons
Back
Ribosomes
Front
Read mRNA three bases or 1 codon at
a time and construct the proteins
Back
Codon
Front
A specific sequence of three adjacent bases on a strand of DNA or RNA that provides genetic code information for a particular amino acid
Back
point, frameshift, and silent
Front
What are the 3 types of mutation?
Back
mRNA
Front
Long Straight chain of Nucleotides
Made in the Nucleus
Copies DNA & leaves through nuclear pores
Contains the Nitrogen Bases A, G, C, U ( no T )
Back
Translation
Front
the process of decoding the mRNA into a polypeptide chain
Back
Insertion mutation
Front
An extra nucleotide is inserted into the DNA
bases are added to the DNA sequence
Back
Introns
Front
non-functional segments of DNA that are snipped out of the chain
Back
missesnse mutation
Front
= DNA codes for the wrong Amino Acid
A single base pair is changed to cause substitution of a different amino acid.
Back
Deletion mutation
Front
A nucleotide is removed from the DNA
part of the DNA is missing.
Back
A protein
Front
What is the end product of protein synthesis?
Back
protein synthesis
Front
The production or synthesis of polypeptide chains (proteins)
Two phases: Transcription & Translation
mRNA must be processed before it leaves the nucleus of eukaryotic cells
Back
Transcription
Front
The process of copying the sequence of one
strand of DNA, the template strand
mRNA copies the template strand
Requires the enzyme RNA Polymerase
Back
tRNA
Front
Clover-leaf shape
Single stranded molecule with attachment site at one end for an amino acid
Opposite end has three nucleotide bases called the anticodon
Back
Point mutation
Front
involve a chemical change in just one
base pair
Back
Exons
Front
segments of DNA that code for proteins, that are rejoined by the enzyme ligase
Back
rRNA
Front
A single strand 100 to 3000 nucleotides long
Globular in shape
Made inside the nucleus of a cell
Associates with proteins to form ribosomes
Site of protein Synthesis
Back
DNA
Front
Sugar deoxyribose
Base Thymine (T)
Double stranded
CANNOT leave nucleus
Back
Frameshift mutation
Front
change the entire amino acid
sequence after the point of the mutation.