Block Test 3: Session 11: Opioids: Objective C

Block Test 3: Session 11: Opioids: Objective C

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Section 1

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Which adverse effect is the major cause of fatality associated with opioid use?

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Last updated

6 years ago

Date created

Mar 1, 2020

Cards (10)

Section 1

(10 cards)

Which adverse effect is the major cause of fatality associated with opioid use?

Front

Respiratory depression

Back

What agent can reverse opioid-induced respiratory depression?

Front

Naloxone

Back

How is opioid induced constipation treated?

Front

Laxatives

Back

Does tolerance develop to the constipating effects of opioids?

Front

No

Back

How does this agent work?

Front

Competitive antagonist of opioid receptors

Back

At what anatomical target do opioids act is to produce nausea/ vomitting?

Front

MOR in area postrema

Back

What are 2 ways that opioid-induced nausea/vomiting can be reduced?

Front

Antiemetics and tolerance

Back

In addition to withdrawal and dependence, what are three other adverse effects of opioid analgesia therapy

Front

Respiratory depression, nausea, constipation

Back

What are some approaches for managing opioid tolerance development?

Front

Drug holidays, interrupted dosing schedules, drug rotation

Back

At what pathways do opioids act to produce rewarding effects associated with addiction?

Front

Reward pathways like VTA-nucleus accumbens

Back