Block Test 2: Session 9: Antiepileptics: Objective C

Block Test 2: Session 9: Antiepileptics: Objective C

memorize.aimemorize.ai (lvl 286)
Section 1

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what are 4 types of CNS effects that AEDs can produce, and which is the most common?

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Last updated

7 years ago

Date created

Mar 1, 2020

Cards (11)

Section 1

(11 cards)

what are 4 types of CNS effects that AEDs can produce, and which is the most common?

Front

sedative (most common), motor/sensory effects, cognitive effects, psychiatric effects

Back

name two AEDs which are rarely-used because of their irreversible side effects

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vigabatrin (permanent loss of vision) felbamate (lethal hepatic failure)

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side effects of phenytoin

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-hirsutism (growth of excess unwanted body hair) -coarsened facial features -gingival hyperplasia (gums grow over and cover up your teeth)

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AEDs can produce

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irreversible side effects

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side effects of valproate

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-weight gain -metabolic syndrome -hair loss -easy bruising

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CNS side effects usually are

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dose-related and reversible

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CNS side effects are

Front

very common with AEDs

Back

newer AEDs are more often

Front

enzyme-inhibitors

Back

4 reasons why DDIs with AEDs are especially problematic

Front

1. AEDs are used chronically 2. AEDs are often used with other types of drugs 3. AEDs are often used together 4. AEDs are increasingly used for other indications

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older AEDs are more often

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enzyme-inducers

Back

Are AEDs are prone to drug interactions?

Front

yes

Back