Section 1
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reaction seen in patients treated for syphilis
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Last updated
6 years ago
Date created
Mar 1, 2020
Cards (78)
Section 1
(50 cards)
reaction seen in patients treated for syphilis
Jarisch Herxheimer reaction
2 possible Rx for Chlamydia
Azithromycin 1 oral dose Doxycycline 2x/day for 1w
Reactive arthritis is seen in
Chlamydia infections
Cytotoxins bind to
NLRs
patient presents with urethral discharge and dysuria and a reddened urethral meatus. DX?
Neisseria Gonorrhea
Dx of N. gonorrhea in female
gram stain and culture
infectious body of chlamydia trachomatis
elementary
Salpingitis is caused by what STI
N. gonorrhea
antibody against ______ is seen in syphilis
Cardiolipin
how does N. gonorrhea inhibit complement cascade
binds to Factor H
Rx of Lymphogranuloma venereum
Doxycycline
typical visible symptoms of tertiary syphilis
Gummas
Rx for chlamydia infection causing PID or epididymitis
2 week course of Doxycycline
vaginal infection that is obligate intracellular
Chlamydia
Diagnostic method for chlamydia
PCR (NAATs) on urine sample
patient with mild dysuria and increased urgency. vaginal itching and discharge. suprapubic tenderness. mucopurulent discharge. culture negative. DX?
Chlamydia infection
most common vaginal microbiota
Lactobacillus
C. trachomatis L1,L2,L3 causes
Lymphogranuloma venereum
STI that is cold sensitive
N. gonorrhea
Chlamydia trachomatis immunotypes associated with STI
D-K
symptoms only in females, not males with chlamydia infection (2)
cervicitis pelvic inflammatory diseases
4 vaginal microbiota
lactobacillus gardnerella vaginalis prevotella candida
wart like lesions on genitalia in secondary syphilis
Condylomata latum
replicative body of chlamydia
reticulate
infectious organisms that causes Syphilis
Treponema pallidum
possible SE of vertical transmission of Gonorrhea
Ophthalmia neonatorum, blindness
3 stages of syphilis and describe them
Primary: infectious, hard, painless ulcer with lymphadenopathy Secondary: flu like, lymphadenopathy, lesions over entire body Tertiary: Neurological, cardio, granulomatous lesions
Rx of Syphilis (2)
Penicillin or Doxy
primary genital lesion with regional lymphadenitis is caused by what bug?
C. trachomatis L1-L3
presence of bacteria and PMNs in joint fluid dx?
purulent arthritis, N. gonorrhea
caused painful lesion on penis
Haemophilus ducreyi
Dx of syphilis
darkfield microscopy
N. Gonorrhea culture can be grown on
chocolate agar thayer martin medium
major reservoir of N. gonorrhea
asymptomatic female
Triad seen in Congenital syphilis
Hutchinson's triad: deafness, notched teeth, keratitis
Charcot Knee is seen in
neurosyphilis
describe Jarisch Herxheimer reaction
antigens released, TNFa and IL-1 causing hypotension and septic shock
decreased bone density is seen in what congenital STI
syphilis
painless lesion on penis is caused by
Syphilis
endotoxins bind to _______ triggering release of ______
TLR4 TNF-a
symptoms of disseminated N. Gonorrhea
petechial rash, purulent arthritis (septic arthritis)
patient presents with fever, lymphadenopathy, and spotty discolorations of his skin. he also has a lesion inside his upper lip with corkscrew shaped organisms under dark field microscopy.
Syphilis
2 prevention meds for ophthalmia neonatorum
silver nitrate eye drops erythromycin ointment
structure of N. Gonorrhoeae
gram negative diplococci
Gram negative like bug with no peptidoglycan
Chlamydia
2 types of bodies in Chlamydia
elementary bodies reticulate bodies
untreated Lymphogranuloma venereum can lead to
genital elephantiasis
Rx of gonorrhea
Ceftriaxone + Azithromycin
endotoxins of N. Gonorrhea
LPS and LOS
Dx of N. gonorrhea in male
gram stain of discharge
Section 2
(28 cards)