Section 1

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Dispersing and clarifying agent

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Date created

Mar 1, 2020

Cards (28)

Section 1

(28 cards)

Dispersing and clarifying agent

Front

Talc

Back

Co-solvent; prevents anti-microbial growth

Front

Alcohol

Back

Label

Front

Store in a tightly closed containers

Back

Container

Front

15 mL clean amber bottle

Back

Uses

Front

Flavoring agent, vehicle for drug preparations

Back

Pourability

Front

Easily pourable

Back

Clear, pleasantly flavoured, sweetened, hydroalcoholic liquids intended for oral use. Less sweet and less viscous than syrups but are more stable

Front

Elixir

Back

Synonyms

Front

Simple Elixir

Back

Category

Front

Pharmaceutical Necessity

Back

The solvent used

Front

Purified water

Back

%EtOh =

Front

= {[(%alcohol used)(volume desired)]/volume of solution} 100

Back

Alcoholic or hydroalcoholic solutions of volatile substances. They contain a high concentration of alcohol, usually over 60% which allows them to better dissolve volatile substances

Front

Spirits

Back

4 methods of preparing spirits

Front

1. Simple solution 2. Solution with maceration 3. Chemical Reaction 4. Distillation

Back

The leaves of the drug to be used is first macerated in purified water to remove water-soluble substances. The macerated leaves are then again macerated in alcohol. The resulting menstrual is then filtered and then added oil and alcohol. The preparation of Peppermint Spirit, USP employs this method.

Front

Solution with Maceration

Back

Appearance

Front

Clear, colorless liquid

Back

_____ can still be added in medicated elixirs to ______ or to ______.

Front

Syrup; increase the solubility of the medicinal agent; decrease the pharmacological effect of the alcohol.

Back

Official Title

Front

Aromatic Elixir, NF

Back

The solutes are dissolved in a suitable solvent by agitation and the solution is left to stand for 12 hours. Most spirits are prepared by this method. One preparation that uses this method is Aromatic Ammonia Spirit, USP

Front

Simple Solution

Back

% Alcohol content

Front

21.0%-23.0%

Back

Sweetener

Front

Syrup

Back

Physical Stability

Front

No foreign materials, no turbidity, no crystallization present

Back

Volatile oils easily ____.

Front

Degrade

Back

Flavoring agent

Front

Essential oils

Back

Main ingredients used in elixirs

Front

Ethanol and water

Back

Packaging Req't

Front

Preserve in tight containers

Back

pH

Front

Neutral

Back

No official spirits make use of this method. The preparation of the no longer official and no longer marketed Ethyl Nitrate Spirit or Sweet Spirit of Nitrate makes use of this method, in which sodium nitrate reacts with a mixture of alcohol and sulfuric acid under cold conditions to form ethyl nitrate.

Front

Chemical reaction

Back

Fermentation is first done and distillation is used to retrieve the spirit. Brandy (fermented juice of grapes) and whisky (fermented mash of wholly or partially germinated malted cereal grains) are prepared this way but they are no longer compendial.

Front

Distillation

Back